When you hear something being referred to as an amphoteric, it’s necessary to understand that this is not a direct chemical at all, but rather a substance that is classified under this name. The prefix amphi-, means both. So when we talk about amphoterics in chemistry, it means that it is a substance that has the ability to be both an acid and a base. The difference is that acids are the type that will donate protons while bases are the ones that accept them. Since these types of chemicals can do either, they are able to be classified as both. Perhaps one of the most popular and well known amphoterics is something you probably have every single day; water. In addition to that, some of the more lesser known amphoterics are going to included bicarbonate ions, Beryllium Hydroxide and plenty of other substances in the world today.